Human placenta extracts Information.
Human placenta extracts are natural substances and shows effects that can replace steroids and reduce adverse effects of steroids, so that human placenta extracts have a wide range of applications including contraceptives, anti-osteoporosis drugs, anti-anemic drugs, therapeutic agents for wasting diseases of muscular atrophy, agents for treating sexual dysfunction, therapeutic agents for wounds, and adipocyte differentiation stimulating agents for improving meat quality of livestock, etc.
The present invention of human placenta extracts relates to a composition containing as an active steroid ingredient a placenta extract from currently discarded placenta of a mammal that is a natural substance and has been proven to have muscle strengthening effects, growth promotion effects similar to that of Glotropin (Human Growth Hormone), and disease therapeutic effects, and a method of preparing the human placenta extract.
However human placenta extract is in a more pure form than anabolic steroids and growth hormone so it is acting in a slightly different and more direct way on the human body. Unfortunately not only the muscles becomes larger using this compound. The hands and the jaw can be expected to grow bigger using this compound.
Anabolic steroid is defined as a testosterone derivative synthesized by changing a chemical structure of testosterone. This is known as a hormone that has a stronger effect than naturally existing testosterone. However, when excessively used, men’s reproductive functions decrease and cardiovascular disorder may occur. Due to such side effects, the Olympic committee in 1964 prohibited sports players from taking anabolic steroid.
In addition, although testosterone is administered to sexually dysfunctional men, testosterone may cause prostate cancer due to the conversion into dihydrotestosterone by 5α-reducing enzyme.
Meanwhile, human placenta extracts is a nutrition supplier that absorbs blood, rich in nutrition and oxygen, from a uterine wall of a mother body and supplies it to a fetus through an umbilical cord. Human Placenta Extracts is also rich in other nutrients including amino acids that are required for a human body and an active peptide that aid pharmaceutical activities, vitamins, nucleic acids, and enzymes. In addition, human placenta extract further includes various growth factors, such as a hepatocyte growth factor, a neuron growth factor, an epithelial growth factor, a fibroblast growth factor, an insulin-like growth factor, or a growth factor for enhancing immunity.
Up to now, protein, lipid, nucleic acids, glycosaminoglycan, amino acids, vitamin, mineral, and the like were isolated and identified from human placenta, and unknown components are expected to be also included in the human placenta extracts.
On this background, the inventors of the present invention studied to develop a natural human placenta extract from which a steroid hormone is obtained in great quantities and which does not cause inherent side effects of steroid, and defined various medical uses of a human placenta extract based on the fact that the placenta extract promotes muscular stem cell proliferation, hematopoietic stem cell proliferation, increases the number of blood cells and an amount of hemoglobin, and expedites differentiation from preadipocytes into adipocyte cells, thereby completing the present invention.
HUMAN PLACENTA EXTRACTS DETAILED DESCRIPTION
The present invention is to most efficiently extract steroid hormones comprising, for example, NPP-100 (nandrolone phenylpropionate), from discarded placenta of a mammal, such as swine, in great quantities for use as a medicament or health food for the prevention and treatment of human disease or stock feed additives.
That is, the present invention provides a composition for the treatment and prevention of: a steroid hormonal disorder-induced disease selected from the group consisting of sexual dysfunction, osteoporosis, wasting muscular disorder, and aging; anemia disorder; or wound disorder, comprising human placenta extracts as an active ingredient.
Technical Solution & Human placenta extract
According to an aspect of the present invention, a composition includes a placenta extract as an active ingredient, wherein the human placenta extracts is obtained by extracting human placenta with an extraction solvent selected from water, C1-4 alcohol, ethylacetate, chloroform, ether, hexane, dichloromethane, and a mixed solvent thereof.
In particular, the human placenta extracts according to the present invention may be used to treat or prevent disorder selected from: steroid hormonal disorder-induced disease selected from the group consisting of sexual dysfunction, osteoporosis, wasting muscular disorder, and aging; anemia disorder; and wound disorder selected from the group consisting of abrasion, laceration, bruise, incised wound, avulsion wound, penetrating wound, contusion, dislocation, sprain, gunshot wound, burn, frostbite, skin ulcer, xeroderma, keratoderma, crack, split, dermatitis, osteonecrosis, pain from dermatophytosis, surgical or vascular disorder wound, cornea wound, bedsore, decubitus, suture site after plastic surgery, wound from spinal injury, gynaecological wound, and chemical wound.
In addition, the placenta extract according to the present invention may promote differentiation from preadipocyte into adipocyte cells.
The placenta extract according to the present invention is a natural substance including high concentrations of anabolic steroid and sex hormone. The placenta extract may reduce side effects that may occur when typical chemically synthesized anabolic steroid and sex hormone drugs are used. In particular, the placenta extract may be used as men’s contraceptives, anti-osteoporosis drugs, anti-anemic drugs, therapeutic agents for wasting diseases of muscular atrophy, agents for treating a decrease in men’s generative functions, therapeutic agents for wounds, or adipocyte differentiation stimulating agents for the improvement of meat quality of livestock.