Mianserin is a tetracyclic antidepressant that has antihistaminic and hypnosedative effects, but almost no anticholinergic effects. Therefore, by using this drug you avoid unpleasant side effects such as dry mouth, constipation, urinary retention, bowel obstruction, dilated pupils, blurred vision, or increased heart rate. By Interacting with serotonin receptors in the central nervous system, the medication works with your body to help you relax and induce a night of more restful sleep. It may cause drowsiness and its effect on easing symptoms or depression is usually noticeable after one to three weeks.
study comparing Mianserin to Diazepam
40 people with major stress and anxiety registered for a trial comparing 14days of treatment with mianserin to thirty to sixty mg each day or valium fifteen to thirty mg every day, then followed by 14days of single-blind placebo. Both the medications ended up being effective anti-anxiety agents, but Mianserin was substantially better in efficacy as determined by the Physician’s Global Rating of Severity of Illness.